New malaria cocktail aims to knock out relapsing p. vivax
NCT ID NCT07533136
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether combining tafenoquine with different antimalarial drugs can better prevent P. vivax malaria from coming back. About 300 adults in Thailand with uncomplicated P. vivax infection will receive one of three drug pairs and be monitored for 6 months. The goal is to find a more effective radical cure that reduces relapse rates.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
tafenoquine (with chloroquine, dihydroartemisinin-piperaquine, or artemether-lumefantrine)
What this could lead to
If successful, this could identify a more effective drug combination to prevent P. vivax malaria from coming back after treatment.
What could go wrong
This is an early-stage trial with only 300 participants, so results may not apply broadly. The study has not yet started recruiting, and the drugs may cause side effects or fail to prevent relapse.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Tha Song Yang Hospital
Ratchathewi, Bangkok, 10400, Thailand
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••