Toothpaste that tames transplant mouth sores?

NCT ID NCT06638879

First seen Nov 06, 2025 · Last updated Apr 24, 2026 · Updated 24 times

Summary

This study tested a special toothpaste containing tacrolimus to help manage painful mouth sores caused by chronic graft-versus-host disease (cGVHD) after a stem cell transplant. Seven patients aged 1 to 40 used the toothpaste alongside their regular medicines. The goal was to see if it could reduce mouth ulcers and improve comfort.

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Contacts and locations

Locations

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

Conditions

Explore the condition pages connected to this study.