New combo therapy targets tough stomach cancer with liver spread

NCT ID NCT07602140

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a mix of treatments—including targeted therapy, immunotherapy, chemotherapy, and procedures that block blood flow to tumors or burn them—as a first treatment for people with a specific type of stomach cancer (HER2-high) that has spread to the liver. About 40 participants will receive this combination to see how well it shrinks tumors and delays cancer growth. The goal is to find a more effective first-line option for this hard-to-treat condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Disitamab vedotin, sintilimab, and chemotherapy drugs

What this could lead to

If it works, this could offer a new first-line treatment option for people with HER2-high gastric cancer that has spread to the liver, potentially shrinking tumors and delaying disease progression.

What could go wrong

This is an early-phase, single-arm study with only 40 participants, so results may not apply broadly. The combination of multiple treatments also raises the risk of serious side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

gastric adenocarcinoma gastric cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••