New eye drug aims to restore sight in inflammatory swelling

NCT ID NCT06990399

Recruiting now Disease control Sponsor: Kodiak Sciences Inc Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 37 times

Summary

This study tests an experimental drug, tabirafusp alfa (KSI-101), given as an eye injection to treat macular edema (swelling in the back of the eye) caused by inflammation. About 600 adults with vision loss from this condition will receive either the drug or a sham injection. The main goal is to see if the drug improves vision over 24 weeks.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

AZ Retina & Vitreous Consultants
RECRUITING

Phoenix, Arizona, 85016, United States
Associated Vitreoretinal and Uveitis Consultants LLC
RECRUITING

Carmel, Indiana, 46032, United States
Austin Retina Associates, PLLC (Austin)
RECRUITING

Austin, Texas, 78705, United States
Austin Retina Associates, PLLC (Round Rock)
RECRUITING

Round Rock, Texas, 78681, United States
California Eye Specialists Medical Group, Inc.
RECRUITING

Pasadena, California, 91107, United States
California Eye Specialists Medical Group, Inc.
RECRUITING

Redlands, California, 92373, United States
California Retina Consultants (Bakersfield)
RECRUITING

Bakersfield, California, 93309, United States
California Retina Consultants (Oxnard)
RECRUITING

Oxnard, California, 93036, United States
Cascade Medical Research Institute
RECRUITING

Springfield, Oregon, 97477, United States
Centro Oftalmologico Metropolitano
RECRUITING

San Juan, 00921, Puerto Rico
Charleston Neuroscience Institute, LLC (Charleston)
RECRUITING

Charleston, South Carolina, 29414, United States
Cleveland Clinic
NOT_YET_RECRUITING

Cleveland, Ohio, 44195, United States
Coastal Eye Surgeons
RECRUITING

Greenwich, Connecticut, 06830, United States
Cumberland Valley Retina Consultants
RECRUITING

Hagerstown, Maryland, 21740, United States
Erie Retina Research
RECRUITING

Erie, Pennsylvania, 16507, United States
Eye Associates of New Mexico, Vision Research Center
NOT_YET_RECRUITING

Albuquerque, New Mexico, 87109, United States
Eye Clinic of Wisconsin
RECRUITING

Wausau, Wisconsin, 54403, United States
Florida Eye Clinic
NOT_YET_RECRUITING

Altamonte Springs, Florida, 32701, United States
Global Research Management, Inc.
RECRUITING

Glendale, California, 91204, United States
Midwest Eye Institute
RECRUITING

Carmel, Indiana, 46032, United States
North Carolina Retina Associates (Cary)
RECRUITING

Cary, North Carolina, 27511, United States
North Carolina Retina Associates (Wake Forest)
RECRUITING

Wake Forest, North Carolina, 27587, United States
Ohio State University
RECRUITING

Columbus, Ohio, 43212, United States
Ophthalmic Consultants of Boston
RECRUITING

Boston, Massachusetts, 02114, United States
Ophthalmology Ltd
RECRUITING

Sioux Falls, South Dakota, 57108, United States
Pacific Northwest Retina (Bellevue)
RECRUITING

Bellevue, Washington, 98004, United States
Pacific Northwest Retina (Silverdale)
RECRUITING

Silverdale, Washington, 98383, United States
Palmetto Retina Center (West Columbia)
RECRUITING

West Columbia, South Carolina, 29169, United States
Research Network Arizona
RECRUITING

Scottsdale, Arizona, 85255, United States
Retina Associates of New York, P.C.
RECRUITING

New York, New York, 10075, United States
Retina Associates, LTD
RECRUITING

Elmhurst, Illinois, 60126, United States
Retina Consultants of Minnesota
RECRUITING

Saint Louis Park, Minnesota, 55416, United States
Retina Consultants of Southern California
RECRUITING

Redlands, California, 92374, United States
Retina Consultants of Texas (Bellaire)
RECRUITING

Bellaire, Texas, 77401, United States
Retina Consultants of Texas (Katy)
RECRUITING

Katy, Texas, 77494, United States
Retina Consultants of Texas (San Antonio)
RECRUITING

San Antonio, Texas, 78240, United States
Retina Consultants of Texas (Woodlands)
RECRUITING

The Woodlands, Texas, 77384, United States
Retina Consultants, PC
RECRUITING

Manchester, Connecticut, 06042, United States
Retina Group of Florida (Ft. Lauderdale)
RECRUITING

Fort Lauderdale, Florida, 33308, United States
Retina Group of New England, PC
RECRUITING

Waterford, Connecticut, 06385, United States
Retina Research Institute of Texas
RECRUITING

Abilene, Texas, 70606, United States
Retina Specialists of Colorado (RSC)
WITHDRAWN

Denver, Colorado, 80222, United States
Retina Vitreous Associates of Florida (St. Petersburg)
RECRUITING

St. Petersburg, Florida, 33711, United States
Retinal Consultants Medical Group Inc
RECRUITING

Sacramento, California, 95841, United States
Rocky Mountain Uveitis
RECRUITING

Denver, Colorado, 80246, United States
St. Mary's Eye Surgery Center (Metropolitan Eye Research and Surgery Institute)
RECRUITING

Palisades Park, New Jersey, 07650, United States
Stanford Byers Eye Institute
NOT_YET_RECRUITING

Palo Alto, California, 94303, United States
Tennessee Retina PC
RECRUITING

Nashville, Tennessee, 37203, United States
Texas Retina Associates (Plano)
RECRUITING

Plano, Texas, 75075, United States
Texas Retina Center
RECRUITING

Houston, Texas, 77030, United States
The Retina Institute
RECRUITING

St Louis, Missouri, 63128, United States
UCLA Stein Eye Institute
RECRUITING

Los Angeles, California, 90095, United States
UCSD/Jacobs Retina Center
RECRUITING

La Jolla, California, 92093, United States
UT Austin
NOT_YET_RECRUITING

Austin, Texas, 78712, United States
Vanderbilt Eye Institute
RECRUITING

Nashville, Tennessee, 37232, United States
Vision Research Solutions
WITHDRAWN

Philadelphia, Pennsylvania, 19141, United States

Conditions

Explore the condition pages connected to this study.

MACULAR EDEMA SECONDARY TO INFLAMMATION