Experimental immune therapy targets Tough-to-Treat sarcomas

NCT ID NCT04044768

Summary

This study is testing whether a personalized immune cell therapy can help control advanced synovial sarcoma or myxoid liposarcoma. Doctors take a patient's own immune cells, genetically modify them to recognize cancer, and infuse them back. The trial will measure how well tumors shrink and monitor side effects in about 52 eligible patients.

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Contacts and locations

Locations

  • Centre Leon Berard

    Lyon, France

  • City of Hope

    Duarte, California, 91010, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Fred Hutch

    Seattle, Washington, 98109, United States

  • Gustave Roussy Cancer Center

    Villejuif, 94805, France

  • Hospital Haut Leveque, CHU Bordeaux

    Pessac, 33604, France

  • Hospital Universitari Vall D'Hebron

    Barcelona, Catalonia, 119-129, Spain

  • Hospital Universitario Virgen del Rocio

    Seville, 41013, Spain

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic Jacksonville

    Jacksonville, Florida, 33612, United States

  • Medical College of WI Froedtert Hospital

    Milwaukee, Wisconsin, 53226, United States

  • Memorial Sloan-Kettering Cancer Center

    New York, New York, 10065, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • National Cancer Institute

    Bethesda, Maryland, 20892, United States

  • Northwestern University Robert H. Lurie Comprehensive Cancer Center

    Chicago, Illinois, 60611, United States

  • Ohio State University

    Columbus, Ohio, 43210, United States

  • Princess Margaret Cancer Centre

    Toronto, Ontario, M5G 2M9, Canada

  • Stanford Cancer Center

    Palo Alto, California, 94305, United States

  • Start Madrid-FJD, Fundación Jimѐnez Díaz

    Madrid, 28040, Spain

  • The Christie NHS Foundation Trust

    Manchester, M20 4BX, United Kingdom

  • UCLH Cancer Clinical Trials Unit

    London, NW1 2PG, United Kingdom

  • University of Colorado

    Aurora, Colorado, 80045, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • Vanderbilt

    Nashville, Tennessee, 37212, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.