Can a new drug combo shrink advanced colorectal tumors?

NCT ID NCT07750041

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This trial is testing whether an investigational drug called SYS6090, when combined with standard treatments like bevacizumab and chemotherapy, can safely and effectively treat advanced colorectal cancer that cannot be removed by surgery. The study includes adults with a specific type of colorectal cancer (pMMR/MSS) who have already tried standard therapies. Researchers will measure how well the combination works, including tumor shrinkage and how long patients live without the disease progressing.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
SYS6090 (an investigational drug) combined with bevacizumab and/or chemotherapy
What this could lead to
If successful, this combination could offer a new treatment option for people with advanced colorectal cancer that has not responded to standard therapies.
What could go wrong
This is an early-phase trial, so the safety and effectiveness of SYS6090 are not yet established. The combination may cause side effects or may not improve outcomes compared to existing treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fujian Cancer Hospital

    Fujian, Fuzhou, 350014, China