New hope for lung cancer patients when targeted drugs stop working

NCT ID NCT06927986

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This Phase 3 trial tests a new drug called SYS6010 against standard chemotherapy in 380 people with a specific type of advanced lung cancer (EGFR-mutated) that has stopped responding to targeted therapy. The goal is to see if SYS6010 can delay cancer growth better than chemo. Participants are randomly assigned to receive either SYS6010 or a platinum-based chemo combination.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SYS6010

What this could lead to

If it works, this could offer a new treatment option for people with EGFR-mutated lung cancer whose current targeted therapy has stopped working.

What could go wrong

This is an early-stage Phase 3 trial, so results are not yet proven. The drug may not work better than chemotherapy or could have unexpected side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for EGFR-MUTATED LOCALLY ADVANCED OR METASTATIC NSCLC are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shanghai Chest Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, 200030, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••