New shot aims to slash Sky-High cholesterol in rare genetic disease

NCT ID NCT07591298

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 2 trial tests an injection called SYH2070 in 18 Chinese adults with homozygous familial hypercholesterolemia (HoFH), a rare genetic condition causing extremely high cholesterol. Participants receive the drug for 48 weeks to see if it safely lowers their LDL cholesterol levels. The study is not yet recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
SYH2070 injection
What this could lead to
If it works, this could offer a new treatment option to lower dangerously high cholesterol in people with homozygous familial hypercholesterolemia.
What could go wrong
This is an early Phase 2 trial with only 18 participants, so results may not apply broadly. The drug may not effectively lower cholesterol or could cause side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

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