New hope for Hard-to-Treat cancers: experimental drug SY-9453 enters human testing

NCT ID NCT07469982

First seen Mar 18, 2026 · Last updated May 14, 2026 · Updated 11 times

Summary

This early-phase study tests a new drug called SY-9453 in people with advanced solid tumors that have a specific genetic change (MTAP deletion). The main goals are to check the drug's safety, find the best dose, and see if it helps shrink tumors. About 122 adults whose cancer has worsened after standard treatments will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shanghai East Hospital

    RECRUITING

    Shanghai, China

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.