New hope for hepatitis delta: can switching drugs clear the virus?

NCT ID NCT07454837

First seen Mar 10, 2026 · Last updated May 15, 2026 · Updated 11 times

Summary

This study tests whether switching from the current drug bulevirtide to a new one called brelovitug can better control chronic hepatitis Delta. About 120 adults who have been on bulevirtide for at least 6 months will take brelovitug and be monitored for 24 weeks. The main goal is to see if the virus becomes undetectable, while also checking for side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Barts Health NHS Trust

    RECRUITING

    London, E12AT, United Kingdom

  • CHU Toulouse Hospital Rangueil, Toulouse

    RECRUITING

    Toulouse, 31400, France

  • CHU de Bordeaux

    RECRUITING

    Bordeaux, 33076, France

  • Castle Hill Hospital

    RECRUITING

    Cottingham, Yorkshire, HU165JQ, United Kingdom

  • Centrul Medical Unirea S.R.L

    RECRUITING

    Iași, Lasi, 700023, Romania

  • Chelsea and Westminster Hospital

    RECRUITING

    London, SW109NH, United Kingdom

  • Clinical Hospital for Infectious and Tropical Diseases Dr. Victor Babes

    RECRUITING

    Bucharest, 030303, Romania

  • Fakultni Nemocnice Brno (University Hospital Brno)

    RECRUITING

    Brno, 62500, Czechia

  • Goethe University Frankfurt

    RECRUITING

    Frankfurt, 60323, Germany

  • Hospital Beaujon

    RECRUITING

    Clichy, 92110, France

  • Hospital Clinic I Provincial De Barcelona

    RECRUITING

    Barcelona, 08036, Spain

  • Institut klinicke a experimentalni mediciny- IKEM (Institute for Clinical and Experimental Medicine)

    RECRUITING

    Prague, 14021, Czechia

  • King's College Hospital NHS Foundation Trust

    RECRUITING

    London, SE5 9RS, United Kingdom

  • Klin Med Ltd. (KLIN MED s.r.o.)

    RECRUITING

    Prague, 12000, Czechia

  • Manchester University Nhs Foundation Trust

    RECRUITING

    Manchester, M13 9WL, United Kingdom

  • Medical University of Graz

    RECRUITING

    Graz, 8010, Austria

  • Medizinische Hochschule Hannover

    RECRUITING

    Hanover, 30625, Germany

  • National Institute Of Infectious Diseases Prof. Dr. Matei Bals

    RECRUITING

    Bucharest, 21105, Romania

  • Spitalul Clinic de Boli Infectioase Constanta

    RECRUITING

    Constanța, 900709, Romania

  • Universitatsmedizin Rostock

    RECRUITING

    Rostock, 18057, Germany

  • University Hospital of Dusseldorf

    RECRUITING

    Düsseldorf, 40225, Germany

  • Vall d'Hebron Hospital

    RECRUITING

    Barcelona, 08035, Spain

Conditions

Explore the condition pages connected to this study.