Narcolepsy drug switch could lower blood pressure

NCT ID NCT05869773

First seen Apr 24, 2026 · Last updated May 15, 2026 · Updated 3 times

Summary

This study measured how blood pressure changed when 155 adults with narcolepsy switched from a high-sodium medicine (sodium oxybate) to a low-sodium version (Xywav). The goal was to see if the switch lowered blood pressure. Participants were already taking the high-sodium drug and then changed to the low-sodium one for the study.

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Contacts and locations

Locations

  • Abington Neurological Associates, LTD

    Abington, Pennsylvania, 19001, United States

  • Advanced Respiratory and Sleep Medicine, PLLC

    Huntersville, North Carolina, 28078, United States

  • Antwerp University Hospital (UZA)

    Edegem, 2650, Belgium

  • Azienda Ospedaliera Universitaria Policlinico Tor Vergata

    Roma, 00133, Italy

  • Bogan Sleep Consultants, LLC

    Columbia, South Carolina, 29201, United States

  • Bryan Medical Center

    Lincoln, Nebraska, 68506, United States

  • CHU Nantes - Hôtel Dieu

    Nantes, Loire Atlantique, 44093, France

  • CHU de Grenoble - Hôpital Albert Michallon

    Grenoble, Isere, 38043, France

  • Clinical Research of Rock Hill

    Rock Hill, South Carolina, 29732, United States

  • FWD Clinical Research

    Boca Raton, Florida, 33486, United States

  • Florida Pediatric Research Institute, LLC

    Orlando, Florida, 32804, United States

  • FutureSearch Trials of Neurology

    Austin, Texas, 78731, United States

  • Henderson Clinical Trials LLC

    Henderson, Nevada, 89052, United States

  • Hopital Gui de Chauliac

    Montpellier, Herault, 34295, France

  • Hospital General de Castellon

    Castellon, 12004, Spain

  • Hospital Universitari Vall d'Hebron

    Barcelona, 08035, Spain

  • Hospital Universitario Araba - Sede Santiago

    Vitoria-Gasteiz, Alava, 01004, Spain

  • Hospital Universitario Clinico San Carlos

    Madrid, 28040, Spain

  • IRCCS Istituto de Scienze Neurologiche di Bologna (ISNB)

    Bologna, 40139, Italy

  • Intrepid Research, LLC

    Cincinnati, Ohio, 45245, United States

  • Long Beach Research Institute

    Lakewood, California, 90805, United States

  • M3 Wake Research

    Encino, California, 91436, United States

  • Meris Clinical Research, LLC

    Brandon, Florida, 33511, United States

  • Neurocare, Inc

    Newton, Massachusetts, 02459, United States

  • OHSU Hospital

    Portland, Oregon, 97239, United States

  • Ocean Wellness Center

    Miami, Florida, 33169, United States

  • Ohio Sleep Medicine and Neuroscience

    Dublin, Ohio, 43017, United States

  • Ospedale San Raffaele (San Raffaele Turro)

    Milan, 20127, Italy

  • Private Practice RESPISOM Namur

    Namur, 5101, Belgium

  • SDS Clinical Trials, Inc.

    Santa Ana, California, 92705, United States

  • Saltzer Medical Group

    Nampa, Idaho, 83686, United States

  • Science 37

    Culver City, California, 90230, United States

  • Serenity Research Center LLC

    Miami, Florida, 33176, United States

  • Sleep Practitioners, LLC

    Macon, Georgia, 31210, United States

  • Sleep Therapy & Research Center

    San Antonio, Texas, 78229, United States

  • So Cal Clinical Research

    Huntington Beach, California, 92647, United States

  • Sparrow Health System

    Lansing, Michigan, 48911, United States

  • Stanford School of Medicine

    Redwood City, California, 94063, United States

  • TriValley Sleep Center

    San Ramon, California, 94583, United States

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio, 44106, United States

  • University of Louisville

    Louisville, Kentucky, 40202, United States

  • University of Maryland Medical Center

    Baltimore, Maryland, 21201, United States

  • Velocity Clinical Research, Greenville

    Greenville, South Carolina, 29615, United States

Conditions

Explore the condition pages connected to this study.