New trial tests which immunotherapy combo best battles melanoma before surgery

NCT ID NCT06794775

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests two different immunotherapy treatments given before surgery for stage III melanoma that can be removed. One group gets a single drug (PD-1 blocker), the other gets a two-drug combo (PD-1 and CTLA-4 blockers). The combo may work better but also has more side effects. About 128 adults with resectable stage III melanoma will take part.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Karolinska University Hospital

    RECRUITING

    Stockholm, Sweden

  • Sahlgrenska University Hospital

    RECRUITING

    Gothenburg, Sweden

  • Skane University Hospital

    RECRUITING

    Lund, Sweden