New lung drug faces off against standard treatment in major trial

NCT ID NCT07284602

Recruiting now Disease control Sponsor: PureTech Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study tests a new drug, LYT-100, against an existing one (pirfenidone) for idiopathic pulmonary fibrosis, a lung disease that gets worse over time. About 1,100 adults will take either drug three times daily for up to a year, and researchers will measure how well their lungs function. The goal is to see if LYT-100 slows lung decline better than the current treatment.

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Conditions

The condition(s) this trial relates to.

idiopathic pulmonary fibrosis lung disorder pulmonary fibrosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IDIOPATHIC PULMONARY FIBROSIS (IPF)

Contacts and locations

Locations

Clinical Research Associates of Central PA
RECRUITING

DuBois, Pennsylvania, 15801, United States
Clinical Research of Rock Hill
RECRUITING

Rock Hill, South Carolina, 29732, United States
Clinical Trials Center of Middle Tennesee LLC
RECRUITING

Franklin, Tennessee, 37067, United States
Infinity Medical Research
RECRUITING

North Dartmouth, Massachusetts, 02747, United States
Palmtree Clinical Research Inc.
RECRUITING

Palm Spring, California, 92262, United States
Paradigm Clinical Research Centers LLC
RECRUITING

Redding, California, 96001, United States
Premier Pulmonary Critical Care and Sleep Medicine
RECRUITING

Denison, Texas, 75020, United States
Renovatio Clinical
RECRUITING

The Woodlands, Texas, 77380, United States
Renovatio Clinical
RECRUITING

Webster, Texas, 77598, United States

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