Researchers track rare genetic disorders to prepare for future treatments

NCT ID NCT06555965

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is observing 600 people of any age with STXBP1 or SYNGAP1 gene mutations to better understand how these disorders affect development, seizures, and quality of life. No treatment is given; instead, researchers will collect data from routine clinical assessments over time. The goal is to gather information needed to design future clinical trials for potential therapies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study will provide crucial data to design future clinical trials for treatments for STXBP1 and SYNGAP1 related disorders.

What could go wrong

This is an observational study with no treatment being tested, so it will not directly improve symptoms. Results depend on consistent participation and data collection over time.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

developmental and epileptic encephalopathy, 4 hereditary disease intellectual disability, autosomal dominant 5

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Children's Hospital Colorado

    RECRUITING

    Aurora, Colorado, 80011, United States

    Contact

    Contact Email: •••••@•••••

  • Stanford Medicine Children's Health

    RECRUITING

    Palo Alto, California, 94304, United States

    Contact

    Contact Email: •••••@•••••

  • Texas Children's Hospital

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Email: •••••@•••••

    Contact

  • The Children's Hospital of Philadelphia

    RECRUITING

    Philadelphia, Pennsylvania, 19403, United States

    Contact

    Contact Email: •••••@•••••

  • Weill Cornell Medicine

    RECRUITING

    New York, New York, 10065, United States

    Contact Email: •••••@•••••

    Contact