New hope for Drug-Resistant lung cancer: experimental pill enters human trials

NCT ID NCT06567015

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new oral drug, STX-241, in people with advanced non-small cell lung cancer that has become resistant to standard targeted therapies. The drug is designed to reach the brain and attack cancer cells with specific genetic changes. The trial aims to find the safest and most effective dose while monitoring side effects and tumor response.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Hôpital de la Timone

    RECRUITING

    Marseille, 13385, France

  • Centre Léon Bérard

    RECRUITING

    Lyon, 69008, France

  • Centro Intergral Oncologico Clara Campal (CIOCC) (START Madrid)

    RECRUITING

    Madrid, 28050, Spain

  • Gustave Roussy

    RECRUITING

    Villejuif, 94800, France

  • Hospital Universitario La Paz

    RECRUITING

    Madrid, 28046, Spain

  • Institut Universitaire du Cancer de Toulouse - Oncopole

    RECRUITING

    Toulouse, 31059, France

  • Institut de Cancérologie de l'Ouest (ICO) - René Gauducheau

    RECRUITING

    Saint-Herblain, 44800, France

  • National Taiwan University Hospital

    RECRUITING

    Taipei, 10002, Taiwan

  • Netherlands Cancer Institute

    RECRUITING

    Amsterdam, 1066 CX, Netherlands

  • Oncology Consultants (OC) - Texas Medical Center - Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

  • Sarah Cannon Research Institute (SCRI) (The SCRI Oncology Research Consortium)

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • Shanghai East Hospital, Tongji University

    RECRUITING

    Shanghai, 200120, China

  • Taipei Veterans General Hospital

    RECRUITING

    Taipei, 11217, Taiwan

  • Tianjin Medical University Cancer Institute and Hospital

    RECRUITING

    Tianjin, 300060, China

  • Universitätsklinikum Carl Gustav Carus Dresden

    RECRUITING

    Dresden, 1307, Germany

  • Vall d'Hebron Institut d'Oncologia

    RECRUITING

    Barcelona, 8035, Spain

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Other studies related to the condition(s) this trial covers.