New pain combo may cut opioid need after hernia repair

NCT ID NCT03907176

First seen Jun 06, 2026 · Last updated Jun 13, 2026 · Updated 2 times

Summary

This study tested whether a non-opioid pain management plan, starting with the drug HTX-011 during surgery, could reduce the need for opioid painkillers after hernia repair. 209 adults having open inguinal hernia surgery took part. The goal was to see if fewer people would need an opioid prescription after the procedure.

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Contacts and locations

Locations

  • Anaheim Clinical Trials, LLC

    Anaheim, California, 92801, United States

  • Baylor University Medical Center

    Dallas, Missouri, 75246, United States

  • Baylor University Medical Center

    Dallas, Texas, 75246, United States

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Cleveland Clinic Fairview

    Cleveland, Ohio, 44111, United States

  • Endeavor Clinical Trials, LLC

    San Antonio, Texas, 78229, United States

  • Hermann Drive Surgical Hospital

    Houston, Texas, 77004, United States

  • Horizon Clinical Research

    La Mesa, California, 91942, United States

  • Houston Methodist Hospital

    Houston, Texas, 77030, United States

  • JBR Clinical Research

    Draper, Utah, 84020, United States

  • M3 Emerging Medical Research, LLC

    Durham, North Carolina, 27704, United States

  • Medical Research of Westchester, Inc

    Miami, Florida, 33144, United States

  • Midwest Clinical Research Center, LLC

    Dayton, Ohio, 45417, United States

  • Montefiore Hutchinson Campus

    The Bronx, New York, 10461, United States

  • Parkview Community Hospital

    Riverside, California, 92503, United States

  • Penn Presbyterian Medical Center

    Philadelphia, Pennsylvania, 19104, United States

  • Plano Surgical Hospital

    Plano, Texas, 75093, United States

  • Professional Health Care of Pinellas

    St. Petersburg, Florida, 33713, United States

  • Rutgers - New Jersey Medical School

    Newark, New Jersey, 07103, United States

  • Sharp Grossmont Hospital

    La Mesa, California, 91942, United States

  • Stony Brook University Hospital

    Stony Brook, New York, 11794, United States

  • Summit Medical Group Oregon-Bend Memorial Clinic

    Bend, Oregon, 97701, United States

  • The Ohio State University Wexner Medical Center - University Hospital

    Columbus, Ohio, 43210, United States

  • Thomas Jefferson University Hospital

    Philadelphia, Pennsylvania, 19107, United States

  • UPMC Passavant

    Pittsburgh, Pennsylvania, 15237, United States

  • UPMC Shadyside Hospital

    Pittsburgh, Pennsylvania, 15232, United States

  • University of California, Irvine Medical Center

    Orange, California, 92868, United States

  • University of Louisville Hospital

    Louisville, Kentucky, 40202, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

  • Yale University School of Medicine

    New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.