HIV prevention shot delivery methods put to the test

NCT ID NCT05374525

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study looked at how to best offer cabotegravir, an HIV prevention shot, in US clinics. About 287 men and transgender men at risk for HIV took part. Researchers compared two ways of rolling out the shot to see which worked better in busy and less busy clinics.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cabotegravir (injectable and oral tablets)

What this could lead to

If successful, this study could show the best way to offer cabotegravir PrEP in clinics, making HIV prevention easier and more accessible for at-risk groups.

What could go wrong

This is a completed Phase 4 implementation study, not a test of the drug itself. It focuses on clinic processes, not new efficacy or safety data, so results may not change current practice.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HIV INFECTIONS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

HIV infectious disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • GSK Investigational Site

    Los Angeles, California, 90036, United States

  • GSK Investigational Site

    San Francisco, California, 94102, United States

  • GSK Investigational Site

    Washington D.C., District of Columbia, 20005, United States

  • GSK Investigational Site

    Miami, Florida, 33140, United States

  • GSK Investigational Site

    Orlando, Florida, 32806, United States

  • GSK Investigational Site

    Pensacola, Florida, 32503, United States

  • GSK Investigational Site

    Sarasota, Florida, 34237, United States

  • GSK Investigational Site

    Bridgeport, Kansas, 06605, United States

  • GSK Investigational Site

    Boston, Massachusetts, 02215, United States

  • GSK Investigational Site

    Columbia, Missouri, 65212, United States

  • GSK Investigational Site

    St Louis, Missouri, 63117, United States

  • GSK Investigational Site

    Rochester, New York, 14607, United States

  • GSK Investigational Site

    The Bronx, New York, 10467, United States

  • GSK Investigational Site

    Philadelphia, Pennsylvania, 19123, United States

  • GSK Investigational Site

    Charleston, South Carolina, 29407, United States

  • GSK Investigational Site

    Harlingen, Texas, 78550, United States

  • GSK Investigational Site

    Seattle, Washington, 98104, United States