New combo therapy aims to control blood cancer relapse after transplant

NCT ID NCT05226455

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 20 times

Summary

This study tests a combination of two drugs (venetoclax and azacitidine) plus donor immune cells in people whose myelodysplastic syndrome or acute myeloid leukemia has returned after a stem cell transplant. The goal is to find the safest dose and see if this approach can improve response. About 55 adults with relapsed disease are taking part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CHU Hôtel Dieu

    Nantes, 44093, France

  • CHU d'Angers

    Angers, 49933, France

  • CHU de Grenoble

    Grenoble, 38043, France

  • CHU de Haut-Lévèque

    Pessac, 33604, France

  • Centre Henri Becquerel

    Rouen, 76038, France

  • Centre Hospitalier Lyon-Sud

    Pierre-Bénite, 69495, France

  • Hôpital Dupuytren

    Limoges, 87042, France

  • Hôpital Saint louis

    Paris, 75010, France

  • Hôpital Saint-Eloi

    Montpellier, 34295, France

  • Hôpital l'Archet I

    Nice, 06200, France

  • IUCT Oncopole

    Toulouse, 31059, France

Conditions

Explore the condition pages connected to this study.