New pill combo offers hope for blood cancer patients ineligible for transplant

NCT ID NCT05782127

First seen Jan 11, 2026 · Last updated Apr 30, 2026 · Updated 17 times

Summary

This study is for people with a high-risk blood disorder called myelodysplastic syndromes (MDS) who have not had treatment before and cannot have a stem cell transplant. Researchers are testing two oral medications, Onureg and Venetoclax, to find the safest and most effective dose. The goal is to control the disease and improve blood counts, but this is not a cure—patients may need ongoing treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CH Annecy Genevois

    Épagny, 74370, France

  • CH Le Mans

    Le Mans, 72037, France

  • CH Lyon sud

    Lyon, 69495, France

  • CH Valence

    Valence, 26000, France

  • CHI Mont-de-Marsan

    Mont-de-Marsan, 40000, France

  • CHU Hôtel Dieu

    Nantes, 44093, France

  • CHU Nîmes - Institut de Cancérologie du Gard

    Nîmes, 30029 cedex 9, France

  • CHU Saint Eloi

    Montpellier, 34295, France

  • CHU d'Amiens Picardie - Site sud

    Amiens, 80054, France

  • CHU d'Angers

    Angers, 49033, France

  • CHU de Grenoble

    Grenoble, 38043, France

  • CHU de Haut-Lévèque

    Pessac, 33604, France

  • CHU de Limoges - Hôpital Dupuytren

    Limoges, 87042, France

  • CHU de Poitiers

    Poitiers, 86021, France

  • CHU de Tours - Hôpital Bretonneau

    Tours, 37000, France

  • Centre Henri Becquerel

    Rouen, 76038, France

  • Hôpital Archet 1

    Nice, 06200, France

  • Hôpital Avicenne

    Bobigny, 93009, France

  • Hôpital Brabois

    Vandœuvre-lès-Nancy, 54500, France

  • Hôpital Cochin

    Paris, 75014, France

  • Hôpital Saint Louis

    Paris, 75010, France

  • Hôpital Saint Vincent de Paul

    Lille, 59020, France

  • Hôpital privé Sévigné

    Cesson-Sévigné, 35510, France

  • IUCT Oncopole

    Toulouse, 31059, France

  • Institut Paoli Calmettes

    Marseille, 13009, France

Conditions

Explore the condition pages connected to this study.