Can a donor corneal disc heal scarred eyes from herpes?
NCT ID NCT05156151
First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time
Summary
This trial tests whether implanting a thin disc of donor cornea tissue — called a stromal lenticule — can improve corneal transparency and vision in people with herpetic stromal keratitis, a herpes infection that scars the cornea. The lenticule contains stem cells and other living cells that may help stabilize and clear the scarred tissue. The study includes 35 participants with low corneal transparency, poor vision, or recurrent flare-ups.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a corneal stromal lenticule (a thin disc of donor cornea tissue containing stem cells, keratocytes, and telocytes) implanted into the eye
- What this could lead to
- If it works, this approach could offer a way to restore corneal clarity and vision in people with scarring from herpes-related eye inflammation.
- What could go wrong
- This is a small, early-stage trial with only 35 participants. The procedure involves eye surgery, which carries risks such as infection, graft rejection, or worsening vision.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Eye Hospital Pristina
Pristina, 10000, Kosovo