New drug aims to shield the brain during stroke surgery

NCT ID NCT05585606

Summary

This study tested whether a drug called Scp776 could protect the brain from damage when given to people undergoing emergency surgery to remove a blood clot after a severe stroke. About 120 participants were randomly assigned to receive either the drug or a placebo (saltwater) alongside their standard surgical treatment. Researchers primarily looked at the safety of the drug and whether it helped patients recover better by measuring their neurological function and disability levels after the stroke.

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Contacts and locations

Locations

  • Augusta University Medical Center

    Augusta, Georgia, 30912, United States

  • Banner University Medical Center /Univ of Arizona

    Tucson, Arizona, 85719, United States

  • Hartford Hospital

    Hartford, Connecticut, 06106, United States

  • HonorHealth Scottsdale Osborn Medical Center

    Scottsdale, Arizona, 85251, United States

  • Houston Methodist Neurological Institute

    Houston, Texas, 77030, United States

  • Jefferson Abington Hospital

    Abington, Pennsylvania, 19001, United States

  • Lennox Hill Hospital

    New York, New York, 10075, United States

  • Marcus Neuroscience Institute

    Boca Raton, Florida, 33486, United States

  • Medical College of Wisconsin and Froedtert Hospital

    Milwaukee, Wisconsin, 53226, United States

  • Mercy Health - St Elizabeth Youngstown Hospital

    Youngstown, Ohio, 44504, United States

  • Mercy Health - St Vincent Medical Center

    Toledo, Ohio, 43608, United States

  • Northshore University Hospital

    Manhasset, New York, 11030, United States

  • Oregon Stroke Center at OHSU

    Portland, Oregon, 97239, United States

  • Penn State Health - M.S. Hershey Medical Center

    Hershey, Pennsylvania, 17033, United States

  • Providence Portland Medical Center

    Portland, Oregon, 97213, United States

  • Providence St. Vincent Medical Center

    West Haven-Sylvan, Oregon, 97225, United States

  • SSM Health DePaul Hospital

    Bridgeton, Missouri, 63044, United States

  • St. Luke's Hospital of Kansas City

    Kansas City, Missouri, 64111, United States

  • The Ohio State University

    Columbus, Ohio, 43210, United States

  • UNM Hospital

    Albuquerque, New Mexico, 87106, United States

  • University of Cincinnati

    Cincinnati, Ohio, 45219, United States

  • University of Miami - Jackson Memorial Hospital

    Miami, Florida, 33136, United States

Conditions

Explore the condition pages connected to this study.