Midlife Women's heart health: stress and sleep may be key
NCT ID NCT06745466
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how daily stress, sleep patterns, and the hormone estrogen affect blood vessel health in women aged 40–55 who are still premenopausal. Researchers will temporarily lower estrogen in 30 volunteers using a drug called ganirelix to see how it changes blood vessel function. The goal is to understand why heart disease risk rises after menopause.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ganirelix acetate
What this could lead to
If successful, this could clarify how estrogen loss during menopause contributes to heart disease risk, pointing toward future prevention strategies.
What could go wrong
This is a small, early-stage mechanistic study (30 participants) that temporarily blocks hormones—it is not testing a treatment. Results may not apply to all women.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
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Contact
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Locations
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University of Delaware
RECRUITINGNewark, Delaware, 19713, United States
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