New hope for blood cancer patients: STP938 trial targets tough cases

NCT ID NCT06786234

Recruiting now Disease control Sponsor: Step Pharma, SAS Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 2 trial tests STP938, a daily pill, in 50 adults with high-risk essential thrombocythaemia who cannot use standard therapy. The goal is to see if it safely lowers high platelet counts and reduces complications like blood clots. Participants take the drug for up to 12 months with regular clinic visits.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: STP938
What this could lead to: If it works, this could offer a new treatment option for people with essential thrombocythaemia who cannot take or do not respond to current therapy.
What could go wrong: This is an early Phase 2 trial with only 50 participants, so results may not apply to everyone. The drug may cause side effects or fail to control platelet counts long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

essential thrombocythemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ESSENTIAL THROMBOCYTHAEMIA

Contacts and locations

Locations

CHU Brest
RECRUITING

Brest, France
CHU Nantes
RECRUITING

Nantes, France
CHU Nice
RECRUITING

Nice, France
CHU Nîmes
RECRUITING

Nîmes, France
Cancer and Haematology Centre, Churchill Hospital
RECRUITING

Oxford, OX3 7LE, United Kingdom
Gustave Roussy
RECRUITING

Villejuif, France
Hôpital Saint-Louis
RECRUITING

Paris, France
Hôpital de la Milétrie, CHU
NOT_YET_RECRUITING

Poitiers, New Aquitaine, 86021, France
Imperial College London / Hammersmith Hospital
RECRUITING

London, United Kingdom
Institut Paoli-Calmettes
RECRUITING

Marseille, France
Royal Hallamshire Hospital
RECRUITING

Sheffield, South Yorkshire, S10 2JF, United Kingdom
Sarah Cannon Research Institute
RECRUITING

London, United Kingdom
University Hospital of Wales
RECRUITING

Cardiff, United Kingdom
University of Southampton Hospital
RECRUITING

Southampton, United Kingdom