Blood test lets doctors cut steroids for kids with GVHD without losing control
NCT ID NCT05090384
First seen May 10, 2026 · Last updated May 15, 2026 · Updated 1 time
Summary
This study tested whether a blood test (GVHD biomarkers) could help doctors safely reduce steroid doses in children with graft-versus-host disease (GVHD) after a bone marrow transplant. Fifty children with low-risk GVHD were enrolled. The goal was to see if a faster steroid taper could maintain treatment response while reducing harmful side effects like infections, bone damage, and growth problems. Results showed that biomarker-guided tapering allowed many children to receive less steroid exposure while still controlling their GVHD.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Boston Children's Hospital Dana Farber Cancer Institute
Boston, Massachusetts, 02115, United States
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Children's Healthcare of Atlanta
Atlanta, Georgia, 30322, United States
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Children's Hospital of Los Angeles
Los Angeles, California, 90027, United States
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Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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Children's National Hospital
Washington D.C., District of Columbia, 20010, United States
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Icahn School of Medicine at Mount Sinai
New York, New York, 10029, United States
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Medical College of Wisconsin / Children's Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Texas Children's Hospital, Baylor College of Medicine
Houston, Texas, 77030, United States
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The Hospital for Sick Children
Toronto, Ontario, M5S, Canada
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Vanderbilt University Medical Center
Nashville, Tennessee, 37235, United States
Conditions
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