Precision radiation may better control spine tumors without extra risk

NCT ID NCT07656883

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial tests a highly targeted radiation technique called stereotactic body radiotherapy (SBRT) against standard radiotherapy for people whose cancer has spread to the spine but has not yet compressed the spinal cord. The goal is to see if SBRT can better prevent tumor growth and spinal cord complications while keeping side effects low. Participants receive either standard radiation or SBRT over five sessions, with close monitoring for safety and tumor control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Stereotactic Body Radiotherapy (SBRT)
What this could lead to
If successful, this precise radiation approach could offer better long-term control of spinal tumors, reducing pain and preventing spinal cord compression.
What could go wrong
This is a mid-stage trial; the higher radiation dose may increase risk of vertebral fractures or spinal cord injury, and benefits over standard care are not yet proven.

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Conditions

The condition(s) this trial relates to.

metastatic carcinoma in the bone Spinal Cord Compression

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHD Vendée

    La Roche-sur-Yon, 85000, France

  • CLCC Ste Catherine - Institut du cancer Avignon/Provence

    Avignon, 84918, France

  • Centre Gillaume le Conquérant

    Le Havre, 76600, France

  • Centre Henri Becquerel

    Rouen, 76038, France

  • Chru Bretonneau

    Tours, 37044, France

  • Chu de Brest

    Brest, 29200, France

  • Clinique Saint Yves

    Vannes, 56000, France

  • Clinique Victor Hugo

    Le Mans, 72000, France

  • Clinique de la Côte d'Emeraude

    St-Malo, 35400, France

  • Clinique mutualiste de l'Estuaire

    Saint-Nazaire, 44600, France

  • Groupe Hospitalier Bretagne Sud (GHBS)

    Lorient, 56322, France

  • Institut de Cancerologie de L'Ouest

    Angers, 49055, France

  • Institut de Cancérologie Radiothérapie Bretillien (ICRB)

    Rennes, 35760, France

  • Institut de Cancérologie de l'Ouest

    Saint-Herblain, 44805, France