Could a heart pump before angioplasty save more heart muscle?

NCT ID NCT03947619

Ongoing Disease control Sponsor: Abiomed Inc. Source: ClinicalTrials.gov ↗

First seen Mar 13, 2026 · Last updated May 12, 2026 · Updated 8 times

Summary

This study tests if using a temporary heart pump (Impella CP) for 30 minutes before opening a blocked artery can reduce heart damage during a heart attack. About 527 people with a first-time anterior heart attack are taking part. The goal is to see if this approach works better than the usual emergency procedure.

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Contacts and locations

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Locations

AdventHealth - Tampa

Tampa, Florida, 33613, United States
Ascension St. John Hospital

Detroit, Michigan, 48236, United States
Azienda Ospedaliera Universitaria Integrata Di Verona

Verona, Veneto, 37126, Italy
Ballad Health - Wellmont CVA Institute

Kingsport, Tennessee, 37660, United States
Baptist Health Research Institute

Jacksonville, Florida, 32207, United States
BayCare Cardiology - Morton Plant Hospital

Clearwater, Florida, 33756, United States
Centennial Medical Center

Nashville, Tennessee, 37203, United States
Christiana Care Health Services

Newark, Delaware, 19718, United States
Emanate Health Intercommunity Hospital / Valley Clinical Trials, Inc.

Covina, California, 91723, United States
George Washington University

Washington D.C., District of Columbia, 20037, United States
Greenville Health System

Greenville, South Carolina, 48201, United States
Hackensack Medical Center

Hackensack, New Jersey, 07601, United States
Hackensack Meridian Mountainside Medical Center

Montclair, New Jersey, 07042, United States
Hamilton Health Science

Hamilton, Ontario, L8L 2X2, Canada
Harefield Hospital

Harefield, United Kingdom
Hartford Health Care

Hartford, Connecticut, 06102, United States
Heart Center Dresden

Dresden, Saxony, 01307, Germany
Heinrich-Braun-Klinikum Zwickau

Zwickau, 08060, Germany
Henry Ford Hospital

Detroit, Michigan, 48202, United States
HonorHealth Research Institute

Scottsdale, Arizona, 82258, United States
Humanitas Clinical & Research Hospital

Rozzano, 20089, Italy
Jersey Shore University Medical Center

Neptune City, New Jersey, 07753, United States
Kettering Medical Center

Kettering, Ohio, 45429, United States
Krankenhaus der Barmherzigen Brüder Trier

Trier, Rhineland-Palatinate, 54290, Germany
Luzerner Kantonsspital

Lucerne, Switzerland
Mercy Iowa Heart

West Des Moines, Iowa, 50266, United States
Methodist Hospital

San Antonio, Texas, 78229, United States
Midwest Cardiovascular Institute

Naperville, Illinois, 60540, United States
NYU School of Medicine

New York, New York, 10016, United States
New Mexico Heart Institute

Albuquerque, New Mexico, 87102, United States
North Shore University Health System

Evanston, Illinois, 60201, United States
Northside Hospital

Atlanta, Georgia, 30342, United States
Northwell Health

Manhasset, New York, 11030, United States
OSF Saint Francis

Peoria, Illinois, 61614, United States
Oklahoma Heart Institute

Tulsa, Oklahoma, 74104, United States
Ospedale Policlinico San Martino

Genoa, Liguria, 16132, Italy
Presbyterian Heart Research Group

Albuquerque, New Mexico, 87106, United States
Prisma Health

Columbia, South Carolina, 29207, United States
Riverside Community Hospital

Riverside, California, 92501, United States
Rutgers Robert Wood Johnson Medical School

New Brunswick, New Jersey, 08901, United States
San Raffaele

Milan, Lombardy, 20132, Italy
Sentara Norfolk General Hospital

Norfolk, Virginia, 23507, United States
Southern Illinois University School of Medicine

Springfield, Illinois, 62794, United States
Spectrum

Grand Rapids, Michigan, 49503, United States
St. Anthony Hospital

Lakewood, Colorado, 80228, United States
Tallahasse Research Institute

Tallahassee, Florida, 32308, United States
The University of Arizona

Tucson, Arizona, 85724, United States
The University of Texas Health Science Center at Houston

Houston, Texas, 77030, United States
Tufts Medical Center

Boston, Massachusetts, 02111, United States
UPMC Presbyterian

Pittsburgh, Pennsylvania, 15213, United States
University Hospital Düsseldorf

Düsseldorf, North Rhine-Westphalia, 40225, Germany
University Hospital Würzburg

Würzburg, Bavaria, 97080, Germany
University Hospital of Marburg

Marburg, 35043, Germany
University Hospitals Cleveland Medical Center

Cleveland, Ohio, 44106, United States
University of Alabama at Birmingham

Birmingham, Alabama, 35294, United States
University of Buffalo Hospital

Buffalo, New York, 14203, United States
University of Calgary

Calgary, Alberta, T2N 4ZA, Canada
University of Ottawa Heart Institue

Ottawa, Ontario, K1Y 4W7, Canada
University of Tennessee Medical Center

Knoxville, Tennessee, 37920, United States
Universitätsklinikum Jena

Jena, D-07747, Germany
Wellstar/Kennestone Hospital

Marietta, Georgia, 30060, United States
West German Heart Center Essen

Essen, North Rhine-Westphalia, 45147, Germany
West Virginia University Hospital

Morgantown, West Virginia, 26506, United States

Conditions

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ST ELEVATION (STEMI) MYOCARDIAL INFARCTION OF ANTERIOR WALL ST ELEVATION (STEMI) MYOCARDIAL INFARCTION OF ANTERIOR WALL