New stem cell approach aims to tame sickle cell and thalassemia

NCT ID NCT05736419

First seen Mar 05, 2026 · Last updated Apr 28, 2026 · Updated 5 times

Summary

This study tests a new way to prepare people with sickle cell disease or beta-thalassemia for a stem cell transplant from a half-matched donor. Before the transplant, patients receive drugs to lower their immune system, which may help prevent serious side effects like graft failure or graft-versus-host disease. The trial enrolls 24 adults and children aged 2 to 50. The goal is to see if this approach reduces treatment-related death or transplant failure within one year.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Memorial Sloan Kettering Bergen (Consent only)

    RECRUITING

    Montvale, New Jersey, 07645, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Monmouth (Consent only)

    RECRUITING

    Middletown, New Jersey, 07748, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Nassau (All protocol activities)

    RECRUITING

    Rockville Centre, New York, 11553, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Suffolk - Commack (Consent only)

    RECRUITING

    Commack, New York, 11725, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Westchester (Consent only)

    RECRUITING

    Harrison, New York, 10604, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering at Basking Ridge (Consent only)

    RECRUITING

    Basking Ridge, New Jersey, 07920, United States

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.