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Softer chemo before transplant may help kids with blood disorders

NCT ID NCT03980769

Recruiting now Disease control Sponsor: Fred Hutchinson Cancer Center Source: ClinicalTrials.gov ↗

First seen Oct 31, 2025 · Last updated Jun 13, 2026 · Updated 30 times

Summary

This study is for people under 50 with non-cancerous blood or immune system diseases that can be treated with a donor stem cell transplant. Doctors want to see if a milder combination of chemotherapy drugs (treosulfan, fludarabine, and thiotepa) can safely prepare the body for new donor cells, with fewer severe side effects than standard high-dose chemo. The main goal is to see if the donor cells successfully take hold and start making healthy blood cells.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fred Hutch/University of Washington Cancer Consortium

    RECRUITING

    Seattle, Washington, 98109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.

NON-NEOPLASTIC HEMATOPOIETIC AND LYMPHOID CELL DISORDER NON-NEOPLASTIC HEMATOPOIETIC AND LYMPHOID CELL DISORDER