Nerve block injection may tame deadly heart storms

NCT ID NCT07211347

Recruiting now Disease control Sponsor: University of Sao Paulo General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a procedure called a stellate ganglion block, where a numbing medicine is injected near nerves in the neck to calm severe, repeated episodes of dangerous heart rhythms (electrical storm). The trial will involve 64 adults with heart disease who have not responded to standard treatments. Half will receive the injection, and the other half will not, to see if it reduces life-threatening heart events by at least 50% within 12 hours.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: stellate ganglion block (lidocaine and bupivacaine injection)
What this could lead to: If it works, this could provide a new, less invasive way to control life-threatening heart rhythm emergencies when standard treatments fail.
What could go wrong: This is a small, early-phase trial with only 64 participants, so results may not apply to everyone. The procedure carries risks like bleeding or nerve damage, and it may not reduce arrhythmias as hoped.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ELECTRICAL STORM STELLATE GANGLION BLOCK VENTRICULAR ARRHYTHMIA

Contacts and locations

Locations

Clinical Research Center of the Heart Institute - University of São Paulo
RECRUITING

São Paulo, São Paulo, 05409011, Brazil

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