New drug stapokibart aims to ease stuffy nose in Non-Allergic rhinitis
NCT ID NCT07240376
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This clinical trial tests whether the drug Stapokibart (CM310) can relieve nasal symptoms in adults with Non-Allergic Rhinitis with Eosinophilia Syndrome (NARES). Ninety participants will receive either Stapokibart or a placebo every two weeks for 12 weeks, while also using a standard nasal spray. The study measures symptom changes and monitors for side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Stapokibart (CM310)
- What this could lead to
- If it works, this could offer a new treatment option for people with NARES, a chronic nasal condition with few effective therapies.
- What could go wrong
- This is a small, early-phase trial with only 90 participants, so results may not apply to everyone. The drug may not improve symptoms more than a placebo, and side effects are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Beijing Tsinghua Changgung Hospital
Beijing, 102218, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Clifford Hospital
Guangzhou, Guangdong, 510000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Eye & Ent Hospital of Fudan University
Shanghai, 200030, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hubei Provincial Hospital of Integrated Chinese and Western Medicine
Wuhan, Hubei, 430010, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Renmin Hospital of Wuhan University
Wuhan, Hubei, 430000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Central Hospital of Wuhan
Wuhan, Hubei, 430014, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Affiliated Hospital of Nanchang University
Nanchang, Jiangxi, 330006, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Tongji hospital, Tongji medical college, Huazhong University of Science and Technology
Wuhan, Hubei, 430000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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West China Hospital, Sichuan University
Chengdu, Sichuan, 610041, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xiangyang Central Hospital
Xiangyang, Hubei, 441106, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Zhongnan Hospital of Wuhan University
Wuhan, Hubei, 430000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact