Could a lactic acid shot ease your back pain?

NCT ID NCT04673461

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested an injection called STA363, made from lactic acid, for people with long-term low back pain from damaged spinal discs. About 110 adults who had not gotten relief from other treatments received either a low dose, a high dose, or a placebo injection into their painful discs. The main goal was to see if the treatment reduced pain over six months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

lactic acid (STA363)

What this could lead to

If it works, this could offer a new injection-based treatment for chronic low back pain caused by damaged discs, potentially reducing pain without surgery.

What could go wrong

This is an early Phase 2 trial with only 110 people, so results may not apply to everyone. The treatment is still experimental, and its long-term safety and effectiveness are not yet proven.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

More trials for these conditions

Other studies related to the condition(s) this trial covers.

Contacts and locations

Locations

  • Alrijne Ziekenhuis Leiderdorp

    Leiderdorp, Netherlands

  • Bekhterev Psychiatry and Neurology Center

    Saint Petersburg, Russia

  • Belgorod Regional Clinical Hospital of Saint Joasaph

    Belgorod, Russia

  • Complejo Hospitalario Ruber Juan Bravo

    Madrid, Spain

  • Hm Puerta Del Sur

    Móstoles, Spain

  • Hospital Quirónsalud Córdoba

    Córdoba, Spain

  • Hospital Universitario Quirónsalud Madrid

    Pozuelo de Alarcón, Spain

  • Kirov State Medical University

    Kirov, Russia

  • Krasnoyarsk Interdistrict Clinical Emergency Hospital

    Krasnoyarsk, Russia

  • LLC MART

    Saint Petersburg, Russia

  • Ochapovsky Regional Clinical Hospital #1

    Krasnodar, Russia

  • Privolzhsky Research Medical University

    Nizhny Novgorod, Russia

  • Regional Clinical Hospital #3

    Chelyabinsk, Russia

  • Rijnstate Hospital Anesthesiology and Pain

    Velp, Netherlands

  • Siberian Research Clinical Center

    Krasnoyarsk, Russia

  • Smolensk Regional Clinical Hospital

    Smolensk, Russia

  • Tula Regional Clinical Hospital

    Tula, Russia