Gene therapy targets chronic nerve pain in new trial

NCT ID NCT06980948

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 27 times

Summary

This study tests a one-time gene therapy called ST-503 for people with hard-to-treat pain from small fiber neuropathy. The therapy aims to block pain signals before they reach the brain. About 27 adults will receive either the gene therapy or a sham procedure to check safety and pain relief over 12 weeks.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CHRONIC NEUROPATHIC PAIN are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Columbia University Irving Medical Center (CUIMC) and New York-Presbyterian Hospital (NYPH)

    RECRUITING

    New York, New York, 10027, United States

    Contact Email: •••••@•••••

  • Dartmouth Hitchcock Medical Center

    NOT_YET_RECRUITING

    Lebanon, New Hampshire, 03766, United States

  • HonorHealth

    RECRUITING

    Scottsdale, Arizona, 85260, United States

    Contact Email: •••••@•••••

  • Johns Hopkins University

    NOT_YET_RECRUITING

    Baltimore, Maryland, 21218, United States

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Email: •••••@•••••

  • The University of California, San Diego

    NOT_YET_RECRUITING

    La Jolla, California, 92093, United States

  • University of Arkansas for Medical Sciences

    RECRUITING

    Little Rock, Arkansas, 72205, United States

    Contact Email: •••••@•••••

  • University of North Carolina Medical Center

    NOT_YET_RECRUITING

    Chapel Hill, North Carolina, 27514, United States

  • University of Utah

    NOT_YET_RECRUITING

    Salt Lake City, Utah, 84112, United States

  • Vanderbilt University

    NOT_YET_RECRUITING

    Nashville, Tennessee, 37235, United States

  • Virginia Commonwealth University

    RECRUITING

    Richmond, Virginia, 23284, United States

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.