Battle of the devices: which tool best mends a broken spleen?
NCT ID NCT05128955
First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time
Summary
This trial compares two medical devices—coils and plugs—used to block blood flow in the splenic artery after a severe spleen injury (grade III or higher). The goal is to see which device works faster and more reliably to stop bleeding without surgery. About 180 people aged 15 and older with such injuries will be randomly assigned to receive one of the two devices during a minimally invasive procedure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Splenic artery embolization with vascular embolic coils or plugs
What this could lead to
If successful, this could identify the best device for stopping bleeding from severe spleen injuries without surgery, potentially improving outcomes and reducing complications.
What could go wrong
This is a mid-stage trial with 180 participants, so results may not apply to all patients. The study focuses on technical success, not long-term recovery, and device failure or complications are possible.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Ohio State University Medical Center
Columbus, Ohio, 43210, United States
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Prisma Health
Greenville, South Carolina, 29615, United States
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The University of Texas Health Science Center at Houston McGovern Medical School
Houston, Texas, 77030, United States
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University of Alabama at Birmingham
Birmingham, Alabama, 35294, United States
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Wake Forest Baptist Medical Center
Winston-Salem, North Carolina, 27157, United States