New inhaled therapy targets Hard-to-Treat cystic fibrosis mutation
NCT ID NCT06429176
First seen May 16, 2026 · Last updated May 16, 2026
Summary
This study tests an experimental inhaled drug called SPL84 in adults with cystic fibrosis who have a specific genetic mutation (3849+10kb C->T). The main goal is to check if the drug is safe and tolerable, and to see early signs it might work. About 64 participants will receive either SPL84 or a placebo weekly for 9 to 12 weeks, with regular clinic visits for monitoring.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Boston Children'S Hospital
NOT_YET_RECRUITINGBoston, Massachusetts, 02115, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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National Jewish Health
RECRUITINGDenver, Colorado, 80206, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Southern California
RECRUITINGLos Angeles, California, 90033, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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