New treatment tested for severe, recurring skin disease flares
NCT ID NCT06013969
Summary
This study is testing a medication called spesolimab for adults who experience repeated, severe flare-ups of generalized pustular psoriasis (GPP), a serious skin condition. Participants receive spesolimab as an intravenous infusion at the start of a flare and may receive a second dose. The goal is to see how well the treatment clears skin pustules and manages symptoms over time, while monitoring for side effects.
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Contacts and locations
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Locations
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ASST degli Spedali Civili di Brescia
Brescia, 25123, Italy
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Chang Gung Memorial Hospital, Linkou
Taoyuan District, 330, Taiwan
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Cliniques Universitaires Saint-Luc
Brussels, 1200, Belgium
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Faculdade de Medicina do ABC
Santo André, 09060-870, Brazil
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Farhat Hached Hospital
Sousse, 4000, Tunisia
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HOP Saint-Louis
Paris, 75010, France
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HOP Trousseau
Chambray-lès-Tours, 37170, France
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Hedi Chaker Hospital, Department of Dermatology
Sfax, 1053, Tunisia
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Hospital Kuala Lumpur
Kuala Lumpur, 50586, Malaysia
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Hospital Pulau Pinang-Pulau Pinang-21953
Georgetown Pulau Pinang, 10990, Malaysia
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Hospital Putrajaya
Putrajaya, 62250, Malaysia
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Hospital Selayang
Batu Caves, 68100, Malaysia
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Hospital Sultan Ismail
Johor Bahru, 81100, Malaysia
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Hospital Sultanah Aminah
Johor Bahru, 80100, Malaysia
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Hospital Universitari Vall D Hebron
Barcelona, 08035, Spain
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Hospital Universitario Evangelico Mackenzie
Curitiba, 80440-220, Brazil
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Hospital Universitario Ramon Y Cajal
Madrid, 28034, Spain
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Klinikum der Universität München AÖR
München, 80337, Germany
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Liverpool Hospital
Liverpool, New South Wales, 2170, Australia
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Maharat Nakhonchiangmai Hospital
Muang Chiang Mai, 50200, Thailand
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National Taiwan University Hospital
Taipei, 100, Taiwan
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National University Hospital-Singapore-42005
Singapore, 119228, Singapore
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Nelson Mandela Academic Clinical Research Unit (NeMACRU)
Mthatha, Eastern Cape, 5099, South Africa
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Nkp Salve Institute of Medical Sciences and Lata Mangeshkar Hospital
Nagpur, 440019, India
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Red River Research Partners, LLC
Fargo, North Dakota, 58103, United States
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SP medical college and associated group of hospitals
Bikaner, 334003, India
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Seoul National University Hospital
Seoul, 03080, South Korea
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Shanghai Skin Disease Hospital
Shanghai, 200000, China
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Shanghai Tenth People's Hospital
Shanghai, 200072, China
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Southern Medical University Dermatology Hospital
Guangzhou, 510091, China
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Srinagarind Hospital
Khon Kaen, 40000, Thailand
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Sunway Medical Centre
Selangor Darul Ehsan, 47500, Malaysia
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University of California Irvine
Irvine, California, 92697, United States
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Universitätsklinikum Frankfurt
Frankfurt am Main, 60596, Germany
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Westmead Hospital
Westmead, New South Wales, 2145, Australia
Conditions
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