New hope for rare skin disease: drug calms severe flare-ups

NCT ID NCT05239039

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 31 times

Summary

This program provided a medicine called spesolimab to 39 people in China with a serious skin disease, generalized pustular psoriasis (GPP), who had no other treatment options. Participants received a single infusion of the drug into a vein, with a possible second dose one week later if needed. The study lasted about 4 months and aimed to control disease flare-ups, not cure the condition.

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Contacts and locations

Locations

  • Beijing Friendship Hospital

    Beijing, 100050, China

  • Dermatology Hospital, Chinese Academy of Medical Sciences

    Nanjing, 210000, China

  • Hangzhou Third People's Hospital

    Hangzhou, 310013, China

  • Shandong Provincial Hospital of Dermatology

    Jinan, 250063, China

  • Shanghai Skin Disease Hospital

    Shanghai, 200000, China

  • Southern Medical University Dermatology Hospital

    Guangzhou, 510091, China

  • The First Hospital of China Medical University

    Shenyang, 110001, China

  • The Second Affiliated Hospital Zhejiang University School of Medicine

    Hangzhou, 310009, China

  • The University of Hong Kong-Shenzhen Hospital

    Shenzhen, 518053, China

  • Tianjin Medical University General Hospital

    Tianjin, 30052, China

  • West China Hospital

    Chengdu, 610041, China

  • Wuhan Union Hospital

    Wuhan, 430022, China

Conditions

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