Promising leukemia drug trial halted early – what it means for patients
NCT ID NCT04817761
First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 23 times
Summary
This study tested a drug called calaspargase pegol in adults aged 22 to over 65 with a specific type of acute lymphoblastic leukemia (ALL) that lacks the Philadelphia chromosome. The goal was to find the right dose and check for side effects. The trial was stopped early, but the information gathered helps researchers understand how the drug works in this patient group.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Baptist Clinical Research Institute
Memphis, Tennessee, 38120, United States
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City of Hope Comprehensive Cancer Center
Duarte, California, 91010, United States
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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Dana Farber Cancer Institute
Weymouth, Massachusetts, 02190, United States
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Duke University
Durham, North Carolina, 27705, United States
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HonorHealth Cancer Transplant Institute
Scottsdale, Arizona, 85258, United States
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Intermountain Healthcare (IHC)
Salt Lake City, Utah, 84143, United States
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Jefferson Health
Philadelphia, Pennsylvania, 19107, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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NYU Langone/Laura and Isaac Perlmutter Cancer Center
New York, New York, 10016, United States
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Northwell Health Cancer Institute
Lake Success, New York, 11042, United States
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Oregon Health & Science University (OHSU)
Portland, Oregon, 97239, United States
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Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Baltimore, Maryland, 21287, United States
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Univeristy of California
Los Angeles, California, 90095, United States
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University of California Irvine Health (UCI Health)
Orange, California, 92868, United States
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University of Chicago Medicine
Chicago, Illinois, 60637, United States
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University of Kansas Cancer Center - Richard and Annette Bloch Cancer Care Pavilion
Westwood, Kansas, 66205, United States
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University of Maryland Greenbaum Cancer Center
Baltimore, Maryland, 21201, United States
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University of Miami Health System - Sylvester Comprehensive Cancer Center
Miami, Florida, 33136, United States
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University of Washington/Seattle Cancer Care Alliance/Fred Hutch
Seattle, Washington, 98109, United States
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West Virginia University Cancer Institute
Morgantown, West Virginia, 26506, United States
Conditions
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