New combo aims to boost transplant success in stubborn leukemia

NCT ID NCT03247088

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 23 times

Summary

This study tests adding the targeted drug sorafenib to standard chemotherapy before a donor stem cell transplant in people with acute myeloid leukemia (AML) that has returned or not responded to treatment. The goal is to find the safest dose and see if it helps patients live longer without the cancer coming back. About 74 adults aged 18 to 70 with a matched donor are being enrolled.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.