New pill combo could boost CAR-T power against tough lymphoma

NCT ID NCT07341191

First seen Jan 16, 2026 · Last updated May 11, 2026 · Updated 19 times

Summary

This study tests whether adding two oral medications (sonrotoclax and zanubrutinib) to standard CAR-T cell therapy can improve outcomes for people with mantle cell lymphoma that has come back or not responded to prior treatment. About 40 adults whose cancer is measurable and who are already scheduled for CAR-T will receive the drug combo before their cell therapy. The main goal is to see if more patients achieve a complete response after CAR-T.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MANTLE CELL LYMPHOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.