New hope for depression-related daytime sleepiness? phase 3 trial underway

NCT ID NCT07484217

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a drug called solriamfetol in adults with major depressive disorder who also struggle with excessive daytime sleepiness. About 508 participants will first receive the drug openly, then some will switch to a placebo to see if the drug helps prevent depressive symptoms from returning. The goal is to find out if this treatment can safely ease sleepiness and improve mood.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MAJOR DEPRESSIVE DISORDER WITH EXCESSIVE DAYTIME SLEEPINESS SYMPTOMS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Disorders of Excessive Somnolence major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Clinical Research Site

    RECRUITING

    Chino, California, 91710, United States

  • Clinical Research Site

    RECRUITING

    Redlands, California, 92374, United States

  • Clinical Research Site

    RECRUITING

    Walnut Creek, California, 94596, United States

  • Clinical Research Site

    RECRUITING

    Jacksonville, Florida, 32256, United States

  • Clinical Research Site

    RECRUITING

    Miami, Florida, 33176, United States

  • Clinical Research Site

    RECRUITING

    Cherry Hill, New Jersey, 08002, United States

  • Clinical Research Site

    RECRUITING

    Toms River, New Jersey, 08755, United States

  • Clinical Research Site

    RECRUITING

    Brooklyn, New York, 11235, United States

  • Clinical Research Site

    RECRUITING

    The Bronx, New York, 10464, United States

  • Clinical Research Site

    RECRUITING

    Cincinnati, Ohio, 45215, United States

  • Clinical Research Site

    RECRUITING

    Portland, Oregon, 97210, United States

  • Clinical Research Site

    RECRUITING

    Memphis, Tennessee, 38119, United States

  • Clinical Research Site

    RECRUITING

    Dallas, Texas, 75243, United States