Could a single dose of sodium oxybate quiet voice tremors?
NCT ID NCT03292458
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a single dose of sodium oxybate can improve voice symptoms in people with spasmodic dysphonia and voice tremor. 117 adults received the drug or a placebo, and researchers measured changes in symptom severity. The goal was to see if the drug could mimic the voice-improving effects of alcohol without the downsides.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Sodium oxybate
- What this could lead to
- If it works, this could point toward a short-term treatment for voice spasms and tremor in people whose symptoms improve with alcohol.
- What could go wrong
- This is a small, early-phase study with only a single dose. The results may not apply to everyone, and sodium oxybate can cause side effects like drowsiness and dizziness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Massachusetts Eye and Ear
Boston, Massachusetts, 02114, United States
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