Could a single dose of sodium oxybate quiet voice tremors?

NCT ID NCT03292458

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a single dose of sodium oxybate can improve voice symptoms in people with spasmodic dysphonia and voice tremor. 117 adults received the drug or a placebo, and researchers measured changes in symptom severity. The goal was to see if the drug could mimic the voice-improving effects of alcohol without the downsides.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Sodium oxybate

What this could lead to

If it works, this could point toward a short-term treatment for voice spasms and tremor in people whose symptoms improve with alcohol.

What could go wrong

This is a small, early-phase study with only a single dose. The results may not apply to everyone, and sodium oxybate can cause side effects like drowsiness and dizziness.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

spasmodic dystonia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Massachusetts Eye and Ear

    Boston, Massachusetts, 02114, United States