Could your own immune cells fight Alzheimer's? new trial launches

NCT ID NCT06189963

Recruiting now Disease control Sponsor: NKGen Biotech, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 2 times

Summary

This early-stage trial is testing whether a personalized natural killer (NK) cell therapy called SNK01 is safe and might help people with moderate Alzheimer's disease. The treatment is made from each patient's own immune cells and given as an IV infusion every three weeks for up to a year. The study will also look for early signs of improvement in thinking, memory, and daily function, as well as changes in brain-related biomarkers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: SNK01 (a personalized natural killer cell therapy made from the patient's own immune cells)
What this could lead to: If it works, this could point toward a new way to slow or improve cognitive decline in moderate Alzheimer's disease by boosting the immune system.
What could go wrong: This is an early phase 1/2 trial with only 36 participants, so it is primarily testing safety. It may not show clear cognitive benefits, and cell therapies can have side effects like infusion reactions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MODERATE ALZHEIMER DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Alzheimer disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MODERATE ALZHEIMER DISEASE

Contacts and locations

Show contact details

Study contacts

Contact

Email: •••••@•••••

Locations

AdventHealth Research Institute
RECRUITING

Orlando, Florida, 32804, United States
Alzheimer's Disease Research Center
RECRUITING

Albany, New York, 12208, United States
Behavioral Research Specialists, LLC
RECRUITING

Glendale, California, 91206, United States
K2 Medical Research
RECRUITING

Maitland, Florida, 32751, United States
Ottawa Memory Clinic
WITHDRAWN

Ottawa, Ontario, K1Z 1G3, Canada
Rutgers Health
RECRUITING

Newark, New Jersey, 07107, United States
Syrentis Clinical Research
RECRUITING

Santa Ana, California, 92705, United States
Valiance Clinical Research
WITHDRAWN

Tarzana, California, 91356, United States