Could a pill stop snake venom? new trial tests oral drugs against antivenom

NCT ID NCT07500233

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests two oral drugs, DMPS and marimastat, to see if they can reduce the harmful effects of snake venom. 504 adults in Brazil and Ghana who have been bitten by a snake will receive either the drug, a placebo, or standard antivenom. The goal is to find a treatment that can be given quickly in rural clinics, potentially saving lives and preventing disability.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

DMPS (unithiol) and marimastat, taken orally

What this could lead to

If successful, these oral drugs could be given sooner than antivenom, potentially reducing disability and death from snakebites, especially in remote areas.

What could go wrong

This is an early phase 2 trial with only 504 participants. The drugs may not work as hoped, could have side effects, or may not be as effective as antivenom.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Snake Bites snakebite envenomation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••