AI could spot hidden heart disease without extra needles

NCT ID NCT07676097

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study tests whether an artificial intelligence system called AngioAI+ can accurately diagnose two types of coronary artery disease using standard angiogram images. The research involves 620 adults with suspected coronary artery disease who are already scheduled for an angiogram. The AI's results will be compared to traditional invasive measurements to see if it can reliably detect blockages and microvascular disease, potentially reducing the need for additional procedures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

AngioAI+ software (artificial intelligence diagnostic tool)

What this could lead to

If successful, this AI tool could help doctors diagnose coronary artery disease and microvascular problems without extra invasive tests, making diagnosis faster and safer.

What could go wrong

This is an observational study testing the software's accuracy against existing methods. The AI may not perform as well in real-world settings or on all patient types.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder Microvascular Angina nonobstructive coronary artery disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ascension Saint Thomas

    Nashville, Tennessee, 37205, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Christ Hospital

    Cincinnati, Ohio, 45219, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Minneapolis Heart

    Minneapolis, Minnesota, 55407, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • New York University

    New York, New York, 10016, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Northwell Health

    New York, New York, 10075, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Palo Alto Veterans Administration Hospital

    Palo Alto, California, 94304, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Stanford University

    Palo Alto, California, 94304, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Valley Health System

    Paramus, New Jersey, 07652, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Washington Hospital Center

    Washington D.C., District of Columbia, 20010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact