AI could spot hidden heart disease without extra needles

NCT ID NCT07676097

Not yet recruiting Diagnosis Sponsor: AngioInsight Source: ClinicalTrials.gov ↗

First seen Jun 30, 2026 · Last updated Jul 14, 2026 · Updated 3 times

Summary

This study tests whether an artificial intelligence system called AngioAI+ can accurately diagnose two types of coronary artery disease using standard angiogram images. The research involves 620 adults with suspected coronary artery disease who are already scheduled for an angiogram. The AI's results will be compared to traditional invasive measurements to see if it can reliably detect blockages and microvascular disease, potentially reducing the need for additional procedures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: AngioAI+ software (artificial intelligence diagnostic tool)
What this could lead to: If successful, this AI tool could help doctors diagnose coronary artery disease and microvascular problems without extra invasive tests, making diagnosis faster and safer.
What could go wrong: This is an observational study testing the software's accuracy against existing methods. The AI may not perform as well in real-world settings or on all patient types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder Microvascular Angina nonobstructive coronary artery disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE OR CHRONIC CORONARY ARTERY DISEASE NON-OBSTRUCTIVE CORONARY DISEASE

Contacts and locations

Locations

Ascension Saint Thomas

Nashville, Tennessee, 37205, United States
Christ Hospital

Cincinnati, Ohio, 45219, United States
Minneapolis Heart

Minneapolis, Minnesota, 55407, United States
New York University

New York, New York, 10016, United States
Northwell Health

New York, New York, 10075, United States
Palo Alto Veterans Administration Hospital

Palo Alto, California, 94304, United States
Stanford University

Palo Alto, California, 94304, United States
Valley Health System

Paramus, New Jersey, 07652, United States
Washington Hospital Center

Washington D.C., District of Columbia, 20010, United States