Can a silver coating make Kids' cavity treatment more effective?
NCT ID NCT07792551
First seen Aug 28, 2026 · Last updated Aug 28, 2026
Summary
This trial compares two minimally invasive ways to treat cavities in children's back baby teeth. The standard Hall Technique seals the cavity with a stainless steel crown, without drilling or numbing. The SMART Hall technique adds a silver diamine fluoride (SDF) coating before sealing, which may help stop bacteria and remineralize the tooth. Researchers will see if the silver version leads to better clinical and X-ray outcomes in children aged 4 to 8.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Silver diamine fluoride (SDF) applied before placing a stainless steel crown, compared with the conventional Hall Technique without SDF.
- What this could lead to
- If adding SDF improves success, it could offer a more effective, child-friendly way to treat cavities in baby molars without drilling or needles.
- What could go wrong
- This is a small, early-stage trial, and the added benefit of SDF may not be significant. There is also a risk of tooth discoloration from SDF.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Oct 2026
An estimate. Start dates often move.
- Expected to finish
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Oct 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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4 to 8 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient-related inclusion criteria: 1. Children aged 4 to 8 years old. 2. One surface carious lesion. 3. No signs and symptoms. (e.g., no tooth pain) 4. Presence of one or more primary molar(s) with deep carious dentine. Tooth-related eligibility criteria: 1. Presence of active cavitated carious lesions that can be removed by an excavator are accessible with hand instruments. 2. Vital pulp with symptom-free or reversible pulpitis. 3. No spontaneous/prolonged pain or percussion pain. 4. No abnormal mobility or signs of infection (swelling, fistula, abscess). 5. Sufficient tooth structure for stainless steel crown retention. 6. Deep caries lesions radiographically extend through at least the inner half of the dentine. 7. Presence of a clear band of normal-appearing dentine between the carious lesion and the pulp in a bitewing radiograph. 8. More than 2/3 of the roots remaining. 9. No internal/external resorption or periapical/furcation pathology. Exclusion Criteria: * 1\. Presence of severe systemic medical conditions (e.g., uncontrolled diabetes, immunodeficiency disorders). 2\. Use of medications known to interfere with dental treatment or healing, such as anticoagulants or immunosuppressants. 3\. Presence of extensive dental caries or additional oral pathologies requiring urgent or specialized dental care beyond the scope of the study. 4\. Patients allergic/sensitive to nickel since PMCs contain nickel. 5. Cases with significant space loss or reduced mesio-distal width due to interproximal caries (making crown fitting difficult). 6\. Unaffected dentine between lesion and pulp cannot be confirmed clinically/radiographically. 7\. Presence of extensive dental caries or additional oral pathology requiring urgent or specified dental care beyond scope of study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Faculty of Dentistry, Cairo University, Cairo, Egypt.
Cairo, Cairo Governorate, 11511, Egypt
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Other studies related to the condition(s) this trial covers.
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- No-Drill cavity fix for kids? gel could replace the scary drill