Can a silver coating make Kids' cavity treatment more effective?

NCT ID NCT07792551

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 28, 2026 · Last updated Aug 28, 2026

Summary

This trial compares two minimally invasive ways to treat cavities in children's back baby teeth. The standard Hall Technique seals the cavity with a stainless steel crown, without drilling or numbing. The SMART Hall technique adds a silver diamine fluoride (SDF) coating before sealing, which may help stop bacteria and remineralize the tooth. Researchers will see if the silver version leads to better clinical and X-ray outcomes in children aged 4 to 8.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Silver diamine fluoride (SDF) applied before placing a stainless steel crown, compared with the conventional Hall Technique without SDF.
What this could lead to
If adding SDF improves success, it could offer a more effective, child-friendly way to treat cavities in baby molars without drilling or needles.
What could go wrong
This is a small, early-stage trial, and the added benefit of SDF may not be significant. There is also a risk of tooth discoloration from SDF.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Oct 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

4 to 8 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patient-related inclusion criteria: 1. Children aged 4 to 8 years old. 2. One surface carious lesion. 3. No signs and symptoms. (e.g., no tooth pain) 4. Presence of one or more primary molar(s) with deep carious dentine. Tooth-related eligibility criteria: 1. Presence of active cavitated carious lesions that can be removed by an excavator are accessible with hand instruments. 2. Vital pulp with symptom-free or reversible pulpitis. 3. No spontaneous/prolonged pain or percussion pain. 4. No abnormal mobility or signs of infection (swelling, fistula, abscess). 5. Sufficient tooth structure for stainless steel crown retention. 6. Deep caries lesions radiographically extend through at least the inner half of the dentine. 7. Presence of a clear band of normal-appearing dentine between the carious lesion and the pulp in a bitewing radiograph. 8. More than 2/3 of the roots remaining. 9. No internal/external resorption or periapical/furcation pathology. Exclusion Criteria: * 1\. Presence of severe systemic medical conditions (e.g., uncontrolled diabetes, immunodeficiency disorders). 2\. Use of medications known to interfere with dental treatment or healing, such as anticoagulants or immunosuppressants. 3\. Presence of extensive dental caries or additional oral pathologies requiring urgent or specialized dental care beyond the scope of the study. 4\. Patients allergic/sensitive to nickel since PMCs contain nickel. 5. Cases with significant space loss or reduced mesio-distal width due to interproximal caries (making crown fitting difficult). 6\. Unaffected dentine between lesion and pulp cannot be confirmed clinically/radiographically. 7\. Presence of extensive dental caries or additional oral pathology requiring urgent or specified dental care beyond scope of study.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

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  1. The places running it

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  2. The official record

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  3. A doctor treating you

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Contacts and locations

Locations

  • Faculty of Dentistry, Cairo University, Cairo, Egypt.

    Cairo, Cairo Governorate, 11511, Egypt

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