New cocktail attack: Triple-Drug trial aims to stall liver cancer

NCT ID NCT06880523

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 27 times

Summary

This study compares a three-drug combination (durvalumab, tremelimumab, and lenvatinib) against a two-drug combo (durvalumab and tremelimumab) in people with advanced liver cancer that cannot be removed by surgery. About 140 adults who have not had prior cancer treatment will participate. The goal is to see if adding lenvatinib helps keep the cancer from growing longer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Arthur J.E. Child Comprehensive Cancer Centre

    RECRUITING

    Calgary, Alberta, T2N 5G2, Canada

    Contact Phone: •••-•••-••••

  • BCCA - Vancouver

    RECRUITING

    Vancouver, British Columbia, V5Z 4E6, Canada

    Contact Phone: •••-•••-••••

  • CHUM-Centre Hospitalier de l'Universite de Montreal

    RECRUITING

    Montreal, Quebec, H2X 3E4, Canada

    Contact Phone: •••-•••-••••

  • Juravinski Cancer Centre at Hamilton Health Sciences

    RECRUITING

    Hamilton, Ontario, L8V 5C2, Canada

    Contact

  • Kingston Health Sciences Centre

    RECRUITING

    Kingston, Ontario, K7L 2V7, Canada

    Contact

  • London Health Sciences Centre Research Inc.

    RECRUITING

    London, Ontario, N6A 5W9, Canada

    Contact Phone: •••-•••-••••

  • Ottawa Hospital Research Institute

    RECRUITING

    Ottawa, Ontario, K1H 8L6, Canada

    Contact Phone: •••-•••-••••

  • The Jewish General Hospital

    RECRUITING

    Montreal, Quebec, H3T 1E2, Canada

    Contact Phone: •••-•••-••••

  • Trillium Health Partners - Credit Valley Hospital

    RECRUITING

    Mississauga, Ontario, L5M 2N1, Canada

    Contact Phone: •••-•••-••••

  • University Health Network

    RECRUITING

    Toronto, Ontario, M5G 2M9, Canada

    Contact Phone: •••-•••-••••

  • Waterloo Regional Health Network (WRHN)

    RECRUITING

    Kitchener, Ontario, N2G 1G3, Canada

    Contact

Conditions

Explore the condition pages connected to this study.