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One pill could cure devastating sleeping sickness

NCT ID NCT03087955

COMPLETED ⭐️ CURE ⭐️ Sponsor: Drugs for Neglected Diseases Source: ClinicalTrials.gov ↗

Summary

This study tested a new oral drug called acoziborole as a potential cure for African sleeping sickness (gambiense HAT). 208 patients with either early or late-stage disease received just three tablets as a single dose. Researchers followed patients for 18 months to see if the single treatment successfully cured the infection and was safe.

Contacts and locations

Locations

  • Centre de Traitement de Kimpese

    Kimpese, Bas-Congo Province, Democratic Republic of the Congo

  • Centre de Traitement de Nkara

    Nkara, Bandundu, Democratic Republic of the Congo

  • Centre de Traitement de la THA de Dubreka

    Dubréka, Dubreka, Guinea

  • Hopital Général de Réference de Bandundu

    Bandundu Province, Democratic Republic of the Congo

  • Hôpital Général de Référence Roi Baudouin

    Kinshasa, Democratic Republic of the Congo

  • Hôpital Général de Référence de Bagata

    Bagata, Kwilu, Democratic Republic of the Congo

  • Hôpital Général de Référence de Kwamouth

    Kwamouth, Mai Ndombe, Democratic Republic of the Congo

  • Hôpital Général de Référence de Masi-Manimba

    Masi-Manimba, Kwilu, Democratic Republic of the Congo

  • Hôpital Général de Référence de Ngandajika

    Gandajika, East Kasai, Democratic Republic of the Congo

  • Hôpital Secondaire de Katanda

    Katanda, East Kasai, Democratic Republic of the Congo

  • Hôpital de Dipumba

    Mbuji-Mayi, East Kasai, Democratic Republic of the Congo

  • Hôpital de Référence d'Isangi

    Isangi, Democratic Republic of the Congo