Military study seeks blood clues to Sleep-Pain mystery after surgery
NCT ID NCT03850743
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This observational study enrolled 111 active-duty military members and eligible patients undergoing orthopedic surgery. Researchers collected blood samples and survey data to find biomarkers (like microRNA and cytokines) linked to sleep problems and pain before and after surgery. The goal is to understand why some people develop chronic pain and sleep issues while others recover well. No treatment or drug was tested.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help identify biological markers that predict who will have worse sleep and pain after surgery, potentially guiding future treatments.
What could go wrong
This is an observational study, not a treatment trial. It only looks for patterns in blood samples and surveys, so it won't directly improve health. Results may not apply to non-military populations.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Walter Reed National Military Medical Center
Bethesda, Maryland, 20889, United States