Military study seeks blood clues to Sleep-Pain mystery after surgery
NCT ID NCT03850743
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This observational study enrolled 111 active-duty military members and eligible patients undergoing orthopedic surgery. Researchers collected blood samples and survey data to find biomarkers (like microRNA and cytokines) linked to sleep problems and pain before and after surgery. The goal is to understand why some people develop chronic pain and sleep issues while others recover well. No treatment or drug was tested.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could help identify biological markers that predict who will have worse sleep and pain after surgery, potentially guiding future treatments.
- What could go wrong
- This is an observational study, not a treatment trial. It only looks for patterns in blood samples and surveys, so it won't directly improve health. Results may not apply to non-military populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Walter Reed National Military Medical Center
Bethesda, Maryland, 20889, United States