Battle of the surgical scrubs: which cleaner wins?
NCT ID NCT00799812
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study tested two different ways to clean the skin before surgery to reduce germs. It compared ChloraPrep (applied all at once or one at a time) with Hibiclens and plain water. 335 healthy adults took part, and the goal was to see which method lowered bacteria the most after 10 minutes and 6 hours.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
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335 people
The number who actually took part.
- Started
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Nov 2007
- Finished
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Jun 2008
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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16 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Subjects must read and sign an Informed Consent Form and be cooperative. * Subjects must be in good general health. * Subjects must have skin within 6 inches of the test site that is free of tattoos, dermatoses, abrasions, cuts, lesions, or other skin disorders. Exclusion Criteria: * Use of systemic or topical antimicrobials during the 2-week pretest conditioning period. This restriction includes but is not limited to shampoos, lotions, soaps, baby powders, and materials, such as solvents, acids, or alkalis. * A medical diagnosis of a physical condition, which would preclude participation such as: diabetes, hepatitis, an organ transplant, a medical surgical implant, or an immunocompromised system. * Any medical condition that in the opinion of the investigator would preclude participation. * Bathed in chemically treated pools or hot tubs 2 weeks prior to any microbial sampling. * Used UV tanning lamps 2 weeks prior to any microbial sampling. * Bathing or showering less than 48 hours prior to any microbial sampling. * Known sensitivity to chlorhexidine gluconate. * Known sensitivity to latex (rubber). * Known sensitivity to fragrances. * Pregnant or nursing. * Unwillingness to fulfill the performance requirements of the study. * Subjects who have completed part or all of the study will not be reentered in the study.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Microbiotest
Sterling, Virginia, 20164, United States
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