Sjögren's drug mystery: biopsy study reveals how ianalumab acts on salivary glands

NCT ID NCT05124925

First seen Feb 02, 2026 · Last updated May 16, 2026 · Updated 12 times

Summary

This study looked at how the drug ianalumab affects the salivary glands of people with Sjögren's syndrome, an autoimmune disease causing dry eyes and mouth. Researchers took small tissue samples (biopsies) from 21 adults to measure changes in immune cells and check for side effects. The goal was to understand the drug's mechanism, not to test if it works as a treatment.

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Contacts and locations

Locations

  • Novartis Investigative Site

    Brest, 29200, France

Conditions

Explore the condition pages connected to this study.